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RESEARCH & DEVELOPMENT OPPORTUNITIES

At AbbVie, we invest in new research, technologies and approaches with an entrepreneurial eye. Our R&D professionals are breaking new ground in the research of virology, neuroscience, immunology, oncology and other complex disease areas where unmet clinical needs continue to exist. By focusing our R&D resources where they have the greatest impact on patients, we are able to continually look for opportunities to increase the efficiency of our R&D programme. 


During the past five years, we have more than doubled the number of compounds in our pipeline through a mix of internal development and external collaboration efforts. Our ability to discover and develop new compounds is enhanced by the company’s use of integrated discovery and development project teams, which include chemists, biologists, physicians and pharmacologists who work collaboratively on the same compounds.

ABBVIE'S APPROACH TO RESEARCH & DEVELOPMENT »

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Discovery & Development

Our discovery and development process always begins with the patient. We ask these important questions: How are patient needs not currently being met? How can we improve their treatment options? How can we work toward better outcomes? Starting with patient needs helps us focus our efforts and keeps our eye on our goal: to help patients improve their health and their lives.

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Discovery
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Drug Discovery addresses key unmet medical needs through the identification and validation of therapeutic targets, generation of leads and optimisation of those leads into drug candidates for clinical evaluation. We focus our discovery and development efforts on a core set of therapeutic areas where we have proven expertise and where we believe we can have an even greater impact on the disease and how it is managed. Core areas of opportunity include liver disease, neuroscience, immunology, oncology, renal disease and women's health.

Collaboration is Key

At AbbVie, you’ll find multiple opportunities for scientific and technical employees to collaborate. For example, at our Bioresearch Center in Worcester, Mass., we have a roundtable process that enables bench scientists to share day-to-day observations in their laboratories with our R&D leadership and suggest avenues for additional exploration. We have also established a global online community that enables AbbVie scientists around the world to exchange ideas and best practices. 

Currently, we have state-of-the-art global research facilities in:

  • North Chicago, Ill., USA
  • Redwood City, Ca., USA
  • Worcester, Mass., USA
  • Ludwigshafen, Germany
  • Shanghai, China

Pharmacology
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The department of pharmacology at AbbVie is an integral part of the Discovery Research Unit that focuses on the discovery, identification and validation of novel molecular targets as well as the identification and characterisation of new therapeutic substances.

Integrative pharmacology provides specialised test systems, which profile the effect of novel therapeutics on multiple organ systems. Areas of opportunity include cardiac electrophysiology, cardiovascular, gastrointestinal, respiratory, renal and CNS activity.



CLINICAL RESEARCH

We are devoted to discovering and developing new medicines for patients with unmet medical needs. AbbVie's research operates with a collaborative model that seeks to build the pipeline of discoveries from inside and outside our company walls. AbbVie's current therapeutic areas of interest are:

  • Virology
  • Neuroscience
  • Immunology
  • Oncology
  • Renal Disease
  • Women’s Health

 

Within each of these therapeutic areas, we have various products in development. The products will change over time as compounds progress through our development program. A critical component of medicinal product development is clinical research, which involves conducting clinical trials in humans to evaluate the safety and efficacy of new products. Clinical trials can take place prior to the approval of a drug (pre market) and after the approval of a drug (post market).

EXPERIENCED HIRES »

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