We are advancing research across several neurodegenerative disorders, including Alzheimer’s disease, multiple sclerosis and Parkinson’s disease.

Our Foundational Neuroscience Centre

On 18 May, 2016 we opened a 43,000 square-foot Foundational Neuroscience Centre (FNC) in Cambridge, Massachusetts. At the FNC, we will undergo research to gain a deeper understanding of the biological mechanisms underlying neurodegenerative diseases. Our goal is to identify novel therapeutic approaches for bringing relief to people living with these chronic and debilitating diseases. 

Alzheimer's Disease

As the number of patients and caregivers seeking help from the health care system increases, Alzheimer’s represents a growing challenge for the NHS and society as a whole. Current treatments simply address the symptoms and do nothing to prevent the progression of the disease or reverse the damage. We are collaborating with the world’s leading Alzheimer’s researchers to identify ways of stopping the disease in its earliest stages. Our anti-tau antibody in being investigated to treat Alzheimer’s disease and progressive supranuclear palsy (PSP) and is advancing to phase II development.

Multiple Sclerosis

Multiple sclerosis, or MS, is a progressive chronic disorder of the nervous system that is most often seen in patients between the ages of 20 and 40. In MS, the immune system attacks a protein called myelin, which forms a protective sheet around neurofibres. When myelin is damaged by MS, neurons struggle to communicate, leading to an accumulation of neuronal loss, atrophy and significant disability over time. We are committed to meeting the needs of patients with MS, and we are currently supporting treatment options that promote nerve protection and facilitate neuronal regeneration.   

Parkinson's Disease

Parkinson’s disease is the second most-common neurodegenerative disorder, affecting more than 10 million people worldwide. In addition to our therapy for advanced Parkinson’s, we are currently exploring other pathways that could provide patients with a new method of treatment for this progressive chronic disease. We are also developing a new delivery system to enhance the patient and caregiver experience while administering our existing therapy for Parkinson’s disease.